Clomid is an antiestrogen from the triphenylethylene group. It is classified as a selective estrogen receptor modulator with mixed agonist and antagonist effects.
Why is Clomid popular?
The main reason why the drug has been widely used in bodybuilding is its ability to block the effects of estrogen, which is achieved by binding the active ingredient to receptors in certain tissues. At the same time, Clomid can behave very differently in bone tissue, where, on the contrary, it activates estrogen receptors, which increases its concentration.
In men, the drug acts as an anti-estrogen, preventing the negative feedback of female hormones to the hypothalamus. In addition, it stimulates the increase in the secretion of GnRH (GnRH). All this increases the production of testosterone (main male hormone) by the testicles. These properties prevent the risk of gynecomastia (breast growth in men) and water retention.
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Application for Clomid
The drug is used in medicine for infertility. With a regular supply in the blood, the levels of gonadotropins hormones increase, which play an important role in regulating the functioning of the gonads. These hormones control the levels of testosterone and estrogen in the blood, which determine the development and functioning of the male and female reproductive organs. With an increase in the level of gonadotropins in a woman’s body, ovulation occurs, and therefore the likelihood of becoming pregnant increases.
Application for Clomid
In bodybuilding, Clomid is used in various steroids. The drug has strong anti-estrogenic properties which may benefit athletes.
The fact is that testosterone and some testosterone-derived steroids partially convert to estrogen. High estrogen levels lead to the development of gynecomastia (growth of female breasts) and excessive fluid retention in the body, both of which are side effects in bodybuilding.
Excess fluid increases blood pressure and masks muscle relief. For this reason, professional bodybuilders take diuretics to remove them from the subcutaneous layers when the body dries out.
When the drug is taken during a steroid cycle, it blocks estrogen receptors in the body, preventing it from working. Therefore, it may be a good idea to fight gynecomastia.
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Use in bodybuilding after a course of steroids in PCT
Most of the time Clomid is used by athletes in bodybuilding after a course of PCT steroids. It is used to restore natural testosterone production, which is almost completely suppressed when using anabolic steroids. The degree of suppression is highly dependent on the type of steroid and the dose.
Use in bodybuilding after a course of steroids in PCT
After discontinuation of steroid use, natural testosterone synthesis gradually begins to recover. However, full recovery takes quite a long time: from several months to a year.
PCT is specifically designed to use pharmacology to speed up the process of restoring natural testosterone production. The drug stimulates the release of gonadotropins, which in turn stimulate the natural production of testosterone.
Therefore, the most popular courses include Clomid and Tamoxifen, as well as the peptide hormone human chorionic gonadotropin.
Side effects
Like other drugs, Clomid has its drawbacks:
- inhibits the production of insulin-like growth factor;
- strongly inhibits the function of the testicles;
- increases the secretion of globulin, which binds to human sex hormones;
- the possibility of increasing the concentration of estrogens with systematic use (it is worth distinguishing between the concept of blocking the action of estrogens and increasing their concentration);
- may affect long-term vision.